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HCP1 (SLC46A1) (NM_080669) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC214417L4V
- LentiORF®
-
Lenti ORF particles, SLC46A1 (mGFP-tagged) - Human solute carrier family 46 (folate transporter), member 1 (SLC46A1), 200ul, >10^7 TU/mL
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CNY 10,070.00
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规格
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Specifications
| Product Data | |
| Product Name | HCP1 (SLC46A1) (NM_080669) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | G21; HCP1; PCFT |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_080669 |
| ORF Size | 1377 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC214417).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_080669.2, NP_542400.2 |
| RefSeq Size | 6510 bp |
| RefSeq ORF | 1380 bp |
| Locus ID | 113235 |
| Protein Families | Transmembrane |
| MW | 49.8 kDa |
| Gene Summary | This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes, optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a heme transporter in duodenal enterocytes, and potentially in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene are associated with autosomal recessive hereditary folate malabsorption disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013] |
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