TM6SF2 (NM_001001524) Human Tagged ORF Clone Lentiviral Particle

CAT＃: RC214298L1V

LentiORF^®

Lenti ORF particles, TM6SF2 (Myc-DDK tagged) - Human transmembrane 6 superfamily member 2 (TM6SF2), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Datasheet

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CNY 8,170.00

货期*

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规格

Cited in 4 publications.

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Specifications

Product Data
Product Name	TM6SF2 (NM_001001524) Human Tagged ORF Clone Lentiviral Particle
Vector	pLenti-C-Myc-DDK
ACCN	NM_001001524
ORF Size	1131 bp
Sequence Data	ORF Nucleotide Sequence (showhide) The ORF insert of this clone is exactly the same as(RC214298).
OTI Disclaimer	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq	NM_001001524.2
RefSeq Size	1483 bp
RefSeq ORF	1134 bp
Locus ID	53345
Protein Families	Transmembrane
MW	42.4 kDa
Gene Summary	Regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content (PubMed:24531328, PubMed:24927523). May function as sterol isomerase (PubMed:25566323).[UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (4)

The use of this cDNA Clones has been cited in the following citations:
TM6SF2/PNPLA3/MBOAT7 Loss-of-Function Genetic Variants Impact on NAFLD Development and Progression Both in Patients and in In Vitro Models ,null, Cellular and Molecular Gastroenterology and Hepatology ,PubMed ID 34823063 [TM6SF2]
Perturbation of TM6SF2 Expression Alters Lipid Metabolism in a Human Liver Cell Line ,null, International Journal of Molecular Sciences ,PubMed ID 34575933 [TM6SF2]
TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content ,null, Proceedings of the National Academy of Sciences of the United States of America ,PubMed ID 24927523 [TM6SF2]
Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease ,null, Nature genetics ,PubMed ID 24531328 [TM6SF2]

Documents

Product Manuals
TrueORFs: Open Reading Frame Clones - 10 ug in PrecisionShuttle Vector System pLenti-ORF destination vector Transfection - TurboFectin 8.0 Transfection Reagent Plasmid Preparation - PowerPrep Plasmid Purification Kits
FAQs
TrueORF Clones/PrecisionShuttle Organelle Marker Transfection Reagent
SDS
Lenti SDS

Resources

cDNA 克隆相关资源
Video Tutorial: Clone Selection Guide Product Video: What is TrueORF GOLD and why it is the most popular type of clone Video Tutorial: How to make Lentivirus particles Video Tutorial: Is the Lentivirus Safe Product Brochure: cDNA clones $98 Clones. Download the List of 15,000 Protocol: Lentivirus packaging