CD43 (SPN) (NM_001030288) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC214120L4V
- LentiORF®
-
Lenti ORF particles, SPN (mGFP-tagged) - Human sialophorin (SPN), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 9,975.00
货期*
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规格
经常一起买 (3)
SPN (CD43) mouse monoclonal antibody, clone OTI6A4 (formerly 6A4)
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Specifications
Product Data | |
Product Name | CD43 (SPN) (NM_001030288) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | CD43; GALGP; GPL115; LSN |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001030288 |
ORF Size | 1200 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC214120).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001030288.1 |
RefSeq Size | 6944 bp |
RefSeq ORF | 1203 bp |
Locus ID | 6693 |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | Cell adhesion molecules (CAMs) |
MW | 40.3 kDa |
Gene Summary | This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017] |
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