TRIM5 alpha (TRIM5) (NM_033034) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC212800L2V
- LentiORF®
Lenti ORF particles, TRIM5 (mGFP-tagged) - Human tripartite motif containing 5 (TRIM5), transcript variant alpha, 200ul, >10^7 TU/mL
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CNY 10,545.00
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Specifications
Product Data | |
Product Name | TRIM5 alpha (TRIM5) (NM_033034) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | RNF88; TRIM5alpha |
Vector | pLenti-C-mGFP |
ACCN | NM_033034 |
ORF Size | 1479 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC212800).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_033034.1 |
RefSeq Size | 2990 bp |
RefSeq ORF | 1482 bp |
Locus ID | 85363 |
Domains | zf-B_box, RING, SPRY |
Protein Families | Druggable Genome |
MW | 56.2 kDa |
Gene Summary | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009] |
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