Plasma Kallikrein 1B (KLKB1) (NM_000892) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC211985L3V
- LentiORF®
Lenti ORF particles, KLKB1 (Myc-DDK tagged) - Human kallikrein B, plasma (Fletcher factor) 1 (KLKB1), 200ul, >10^7 TU/mL
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CNY 8,930.00
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规格
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Specifications
Product Data | |
Product Name | Plasma Kallikrein 1B (KLKB1) (NM_000892) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | KLK3; PKK; PKKD; PPK |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_000892 |
ORF Size | 1914 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC211985).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000892.2 |
RefSeq Size | 2245 bp |
RefSeq ORF | 1917 bp |
Locus ID | 3818 |
Domains | APPLE, Tryp_SPc, PAN |
Protein Families | Druggable Genome, Protease |
Protein Pathways | Complement and coagulation cascades |
MW | 71.37 kDa |
Gene Summary | This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016] |
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