IL23 Receptor (IL23R) (NM_144701) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC211477L1V
- LentiORF®
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Lenti ORF particles, IL23R (Myc-DDK tagged) - Human interleukin 23 receptor (IL23R), 200ul, >10^7 TU/mL
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CNY 11,020.00
Cited in 2 publications. |
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CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Product Name | IL23 Receptor (IL23R) (NM_144701) Human Tagged ORF Clone Lentiviral Particle |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_144701 |
ORF Size | 1887 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC211477).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_144701.2 |
RefSeq Size | 2826 bp |
RefSeq ORF | 1890 bp |
Locus ID | 149233 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
MW | 69 kDa |
Gene Summary | The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. [provided by RefSeq, Jul 2008] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
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IL23 induces IL23R recycling and amplifies innate receptor-induced signalling and cytokines in human macrophages, and the IBD-protective IL23R R381Q variant modulates these outcomes
,null,
Gut
,PubMed ID 31097538
[IL23R]
|
Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses
,null,
Proceedings of the National Academy of Sciences of the United States of America
,PubMed ID 21606346
[IL23R]
|
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