Mad (MXD1) (NM_002357) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC210520L1V
- LentiORF®
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Lenti ORF particles, MXD1 (Myc-DDK tagged) - Human MAX dimerization protein 1 (MXD1), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 7,410.00
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规格
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Specifications
Product Data | |
Product Name | Mad (MXD1) (NM_002357) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | BHLHC58; MAD; MAD1 |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_002357 |
ORF Size | 663 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC210520).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_002357.2 |
RefSeq Size | 5630 bp |
RefSeq ORF | 666 bp |
Locus ID | 4084 |
Domains | HLH |
Protein Families | Druggable Genome, Transcription Factors |
MW | 25.3 kDa |
Gene Summary | This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011] |
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