PPM1F (NM_014634) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC210043L4V

  • LentiORF®

Lenti ORF particles, PPM1F (mGFP-tagged) - Human protein phosphatase, Mg2+/Mn2+ dependent, 1F (PPM1F), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 9,975.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name PPM1F (NM_014634) Human Tagged ORF Clone Lentiviral Particle
Synonyms CAMKP; CaMKPase; FEM-2; hFEM-2; POPX2
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_014634
ORF Size 3534 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC210043).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_014634.2
RefSeq Size 5199 bp
RefSeq ORF 1365 bp
Locus ID 9647
Domains PP2C
Protein Families Druggable Genome, Phosphatase
MW 49.7 kDa
Gene Summary The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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