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GPCR MRGX2 (MRGPRX2) (NM_054030) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC209033L3V
- LentiORF®
-
Lenti ORF particles, MRGPRX2 (Myc-DDK tagged) - Human MAS-related GPR, member X2 (MRGPRX2), 200ul, >10^7 TU/mL
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CNY 8,170.00
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规格
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Specifications
| Product Data | |
| Product Name | GPCR MRGX2 (MRGPRX2) (NM_054030) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | MGRG3; MRGX2 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_054030 |
| ORF Size | 990 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC209033).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_054030.2 |
| RefSeq Size | 2130 bp |
| RefSeq ORF | 993 bp |
| Locus ID | 117194 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| MW | 37.1 kDa |
| Gene Summary | Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed:25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction (By similarity). Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.[UniProtKB/Swiss-Prot Function] |
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