RNF185 (NM_152267) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC207827L4V

  • LentiORF®

Lenti ORF particles, RNF185 (mGFP-tagged) - Human ring finger protein 185 (RNF185), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 8,360.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name RNF185 (NM_152267) Human Tagged ORF Clone Lentiviral Particle
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_152267
ORF Size 576 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC207827).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_152267.2
RefSeq Size 3218 bp
RefSeq ORF 579 bp
Locus ID 91445
Domains RING
Protein Families Druggable Genome, Transmembrane
MW 20.5 kDa
Gene Summary E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination of BNIP1 (PubMed:21931693). Acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation (PubMed:27485036). Protects cells from ER stress-induced apoptosis (PubMed:27485036). Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway (PubMed:24019521). Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2 (PubMed:24019521).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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