RAIN (RASIP1) (NM_017805) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC206189L3V
- LentiORF®
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Lenti ORF particles, RASIP1 (Myc-DDK tagged) - Human Ras interacting protein 1 (RASIP1), 200ul, >10^7 TU/mL
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CNY 8,930.00
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Specifications
Product Data | |
Product Name | RAIN (RASIP1) (NM_017805) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | RAIN |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_017805 |
ORF Size | 2889 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC206189).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_017805.2, NP_060275.2 |
RefSeq Size | 3311 bp |
RefSeq ORF | 2892 bp |
Locus ID | 54922 |
Domains | DIL |
MW | 103.5 kDa |
Gene Summary | Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells (By similarity). May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.[UniProtKB/Swiss-Prot Function] |
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