PIM1 (NM_002648) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC205853L1V
- LentiORF®
-
Lenti ORF particles, PIM1 (Myc-DDK tagged) - Human pim-1 oncogene (PIM1), 200ul, >10^7 TU/mL
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CNY 8,170.00
货期*
详询
规格
Cited in 2 publications. |
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经常一起买 (3)
Specifications
Product Data | |
Product Name | PIM1 (NM_002648) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | PIM |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_002648 |
ORF Size | 939 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC205853).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_002648.2 |
RefSeq Size | 2684 bp |
RefSeq ORF | 942 bp |
Locus ID | 5292 |
Domains | pkinase, TyrKc, S_TKc |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase |
Protein Pathways | Acute myeloid leukemia, Jak-STAT signaling pathway |
MW | 35.5 kDa |
Gene Summary | The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
---|
Antiproliferative potential of miR-33a in laryngeal cancer Hep-2 cells via targeting PIM1.
,null,
Head neck
,PubMed ID 30102806
[PIM1]
|
HistoneH3 demethylase JMJD2A promotes growth of liver cancer cells through up-regulating miR372
,null,
Oncotarget
,PubMed ID 28467776
[PIM1]
|
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