Neurotensin Receptor 2 (NTSR2) (NM_012344) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC205343L3V
- LentiORF®
-
Lenti ORF particles, NTSR2 (Myc-DDK tagged) - Human neurotensin receptor 2 (NTSR2), 200ul, >10^7 TU/mL
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CNY 8,930.00
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Specifications
Product Data | |
Product Name | Neurotensin Receptor 2 (NTSR2) (NM_012344) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | NTR2 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_012344 |
ORF Size | 1230 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC205343).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_012344.2 |
RefSeq Size | 1622 bp |
RefSeq ORF | 1233 bp |
Locus ID | 23620 |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Protein Pathways | Neuroactive ligand-receptor interaction |
MW | 45.5 kDa |
Gene Summary | The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq, Jul 2008] |
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