PLOD3 (NM_001084) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC203445L4V
- LentiORF®
Lenti ORF particles, PLOD3 (mGFP-tagged)-Human procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (PLOD3), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
Product Data | |
Product Name | PLOD3 (NM_001084) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | LH3 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001084 |
ORF Size | 2214 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC203445).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001084.4 |
RefSeq Size | 2995 bp |
RefSeq ORF | 2217 bp |
Locus ID | 8985 |
Domains | 2OG-FeII_Oxy, P4Hc |
Protein Pathways | Lysine degradation |
MW | 84.79 kDa |
Gene Summary | The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008] |
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