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TNNI1 (NM_003281) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC203127L2V
- LentiORF®
-
Lenti ORF particles, TNNI1 (mGFP-tagged) - Human troponin I type 1 (skeletal, slow) (TNNI1), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | TNNI1 (NM_003281) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | SSTNI; TNN1 |
| Vector | pLenti-C-mGFP |
| ACCN | NM_003281 |
| ORF Size | 561 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC203127).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_003281.3 |
| RefSeq Size | 6162 bp |
| RefSeq ORF | 564 bp |
| Locus ID | 7135 |
| Domains | Troponin |
| MW | 21.7 kDa |
| Gene Summary | Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. [provided by RefSeq, Jul 2008] |
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