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RNF183 (NM_145051) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC201440L3V
- LentiORF®
-
Lenti ORF particles, RNF183 (Myc-DDK tagged) - Human ring finger protein 183 (RNF183), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | RNF183 (NM_145051) Human Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_145051 |
| ORF Size | 576 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC201440).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_145051.2, NP_659488.1 |
| RefSeq Size | 1237 bp |
| RefSeq ORF | 579 bp |
| Locus ID | 138065 |
| Protein Families | Druggable Genome, Transmembrane |
| MW | 21.7 kDa |
| Gene Summary | Acts as a E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (PubMed:29507230). Triggers apoptosis in response to prolonged ER stress by mediating the polyubiquitination and subsequent proteasomal degradation of BCL2L1 (PubMed:29507230). May collaborate with FATE1 to restrain BIK protein levels thus regulating apoptotic signaling (PubMed:26567849).[UniProtKB/Swiss-Prot Function] |
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