Melanophilin (MLPH) (NM_024101) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC200895L3V
- LentiORF®
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Lenti ORF particles, MLPH (Myc-DDK tagged) - Human melanophilin (MLPH), transcript variant 1, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Product Name | Melanophilin (MLPH) (NM_024101) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | SLAC2-A |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_024101 |
ORF Size | 1800 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC200895).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_024101.5 |
RefSeq Size | 3787 bp |
RefSeq ORF | 1803 bp |
Locus ID | 79083 |
MW | 65.9 kDa |
Gene Summary | This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013] |
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