Wnt3a (NM_009522) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR227165L1V
- LentiORF®
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Lenti ORF particles, Wnt3a (Myc-DDK-tagged) - Mouse wingless-related MMTV integration site 3A (Wnt3a), 200ul, >10^7 TU/mL
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CNY 7,410.00
货期*
详询
规格
Cited in 1 publication. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | Wnt3a (NM_009522) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | vt; Wnt-3a |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_009522 |
ORF Size | 1056 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR227165).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_009522.2, NP_033548.1 |
RefSeq Size | 2791 bp |
RefSeq ORF | 1059 bp |
Locus ID | 22416 |
Gene Summary | Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:26902720). Required for normal embryonic mesoderm development and formation of caudal somites (PubMed:8299937). Required for normal morphogenesis of the developing neural tube (PubMed:8299937). Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro) (PubMed:26902720).[UniProtKB/Swiss-Prot Function] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Activation of the Wnt/β-catenin pathway represses the transcription of the β-amyloid precursor protein cleaving enzyme (BACE1) via binding of T-cell factor-4 to BACE1 promoter.
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology
,PubMed ID 25384422
[Wnt3a]
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