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Vip (NM_011702) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR226907L3V
- LentiORF®
-
Lenti ORF particles, Vip (Myc-DDK-tagged) - Mouse vasoactive intestinal polypeptide (Vip), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Vip (NM_011702) Mouse Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_011702 |
| ORF Size | 513 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR226907).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_011702.2 |
| RefSeq Size | 1527 bp |
| RefSeq ORF | 516 bp |
| Locus ID | 22353 |
| Gene Summary | This gene encodes a neuropeptide of the glucagon/secretin superfamily with potent bronchodilator, immunomodulator and anti-inflammatory properties. The encoded protein is proteolytically processed to generate two structurally similar neuropeptides - vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI). In the digestive tract, VIP stimulates relaxation of enteric smooth muscle, secretion of water and electrolytes, release of insulin and glucagon, and inhibition of gastric acid secretion. In the cardiovascular system, VIP causes coronary vasodilation and stimulates contractility in the heart. Mice lacking VIP exhibit airway hyperresponsiveness and airway inflammation. Male mice lacking VIP exhibit moderate pulmonary arterial hypertension resulting in increased mortality. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015] |
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