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Yod1 (NM_178691) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR226493L3V
- LentiORF®
-
Lenti ORF particles, Yod1 (Myc-DDK-tagged) - Mouse YOD1 OTU deubiquitinating enzyme 1 homologue (S. cerevisiae) (Yod1), 200ul, >10^7 TU/mL
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CNY 8,360.00
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规格
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Specifications
| Product Data | |
| Product Name | Yod1 (NM_178691) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 6330564D18Rik; 9930028C20Rik; Hshin7 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_178691 |
| ORF Size | 1029 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR226493).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_178691.4, NP_848806.2 |
| RefSeq Size | 3843 bp |
| RefSeq ORF | 1032 bp |
| Locus ID | 226418 |
| Gene Summary | Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains. Also able to hydrolyze 'Lys-11'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. May recruit PLAA, UBXN6 and VCP to damaged lysosome membranes decorated with K48-linked ubiquitin chains and remove these chains allowing autophagosome formation.[UniProtKB/Swiss-Prot Function] |
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