Usp19 (NM_001168373) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR226428L3V

  • LentiORF®

Lenti ORF particles, Usp19 (Myc-DDK-tagged) - Mouse ubiquitin specific peptidase 19 (Usp19), transcript variant 4, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 18,905.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Usp19 (NM_001168373) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 8430421I07Rik; AI047774; Zmynd9
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_001168373
ORF Size 3966 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR226428).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001168373.2, NP_001161845.1
RefSeq Size 4722 bp
RefSeq ORF 3969 bp
Locus ID 71472
Gene Summary Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates (By similarity). Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing thier ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Exhibits a preference towards 'Lys-63'-linked ubiquitin chains (By similarity). Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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