Spo11 (NM_001083960) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR226171L3V
- LentiORF®
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Lenti ORF particles, Spo11 (Myc-DDK-tagged) - Mouse sporulation protein, meiosis-specific, SPO11 homolog (S. cerevisiae) (Spo11), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | Spo11 (NM_001083960) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | AI449549; Spo11a; Spo11b |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001083960 |
ORF Size | 1074 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR226171).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001083960.1, NP_001077429.1 |
RefSeq Size | 1602 bp |
RefSeq ORF | 1077 bp |
Locus ID | 26972 |
Gene Summary | Isoform 1: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination (PubMed:26917764). The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2 (PubMed:22346761).[UniProtKB/Swiss-Prot Function] |
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