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Bves (NM_024285) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR225843L3V
- LentiORF®
-
Lenti ORF particles, Bves (Myc-DDK-tagged) - Mouse blood vessel epicardial substance (Bves), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Bves (NM_024285) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | mBVES; Pop1; Popdc1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_024285 |
| ORF Size | 1074 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR225843).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_024285.2 |
| RefSeq Size | 1607 bp |
| RefSeq ORF | 1077 bp |
| Locus ID | 23828 |
| Gene Summary | Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells (PubMed:16188940). Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3 (PubMed:20057356). Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT (PubMed:18541910). Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading (PubMed:11839816). Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density (PubMed:26642364). Is a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury (PubMed:24066022).[UniProtKB/Swiss-Prot Function] |
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