Tm4sf20 (NM_025453) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR224367L4V

  • LentiORF®

Lenti ORF particles, Tm4sf20 (GFP-tagged) - Mouse transmembrane 4 L six family member 20 (Tm4sf20), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 8,360.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Tm4sf20 (NM_025453) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 1810018L02Rik
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_025453
ORF Size 678 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR224367).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_025453.3
RefSeq Size 1503 bp
RefSeq ORF 681 bp
Locus ID 66261
Gene Summary Polytopic transmembrane protein. Inhibits regulated intramembrane proteolysis (RIP) of CREB3L1, inhibiting its activation and the induction of collagen synthesis. In response to ceramide, which alters TM4SF20 membrane topology, stimulates RIP activation of CREB3L1. Ceramide reverses the direction through which transmembrane helices are translocated into the endoplasmic reticulum membrane during translation of TM4SF20, this mechanism is called 'regulated alternative translocation' (RAT) and regulates the function of the transmembrane protein.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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