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Nlrp10 (NM_175532) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR223786L4V
- LentiORF®
-
Lenti ORF particles, Nlrp10 (GFP-tagged) - Mouse NLR family, pyrin domain containing 10 (Nlrp10), 200ul, >10^7 TU/mL
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CNY 12,825.00
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Specifications
| Product Data | |
| Product Name | Nlrp10 (NM_175532) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 6430548I20Rik; Nalp10; Napl10; PAN5; Pynod |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_175532 |
| ORF Size | 2022 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR223786).
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| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_175532.3, NP_780741.1 |
| RefSeq Size | 4483 bp |
| RefSeq ORF | 2022 bp |
| Locus ID | 244202 |
| Gene Summary | Inhibits autoprocessing of CASP1, CASP1-dependent IL1B secretion, PYCARD aggregation and PYCARD-mediated apoptosis but not apoptosis induced by FAS or BID (By similarity). Displays anti-inflammatory activity (By similarity). Required for immunity against C.albicans infection (PubMed:23071280). Involved in the innate immune response by contributing to proinflammatory cytokine release in response to invasive bacterial infection (By similarity). Contributes to T-cell-mediated inflammatory responses in the skin (PubMed:27221772). Plays a role in protection against periodontitis through its involvement in induction of IL1A via ERK activation in oral epithelial cells infected with periodontal pathogens (By similarity). Exhibits both ATPase and GTPase activities (By similarity).[UniProtKB/Swiss-Prot Function] |
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