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Glmn (NM_001161738) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR223429L3V
- LentiORF®
-
Lenti ORF particles, Glmn (Myc-DDK-tagged) - Mouse glomulin, FKBP associated protein (Glmn), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 10,640.00
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Specifications
| Product Data | |
| Product Name | Glmn (NM_001161738) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 9330160J16Rik; AW227515; Fap48; Fap68 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001161738 |
| ORF Size | 1788 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR223429).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001161738.1, NP_001155210.1 |
| RefSeq Size | 2001 bp |
| RefSeq ORF | 1791 bp |
| Locus ID | 170823 |
| Gene Summary | Regulatory component of cullin-RING-based SCF (SKP1-Cullin-F-box protein) E3 ubiquitin-protein ligase complexes. Inhibits E3 ubiquitin ligase activity by binding to the RING domain of RBX1 and inhibiting its interaction with the E2 ubiquitin-conjugating enzyme CDC34. Inhibits RBX1-mediated neddylation of CUL1 (By similarity). Required for normal stability and normal cellular levels of key components of SCF ubiquitin ligase complexes, including FBXW7, RBX1, CUL1, CUL2, CUL3, CUL4A, and thereby contributes to the regulation of CCNE1 and MYC levels (PubMed:22405651). Essential for normal development of the vasculature (PubMed:22405651). Contributes to the regulation of RPS6KB1 phosphorylation (By similarity).[UniProtKB/Swiss-Prot Function] |
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