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Plcz1 (NM_054066) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR223280L4V
- LentiORF®
-
Lenti ORF particles, Plcz1 (GFP-tagged) - Mouse phospholipase C, zeta 1 (Plcz1), 200ul, >10^7 TU/mL
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CNY 12,540.00
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Specifications
| Product Data | |
| Product Name | Plcz1 (NM_054066) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 1700041H07Rik; PLCzeta |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_054066 |
| ORF Size | 1941 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR223280).
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| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_054066.4, NP_473407.2 |
| RefSeq Size | 2182 bp |
| RefSeq ORF | 1944 bp |
| Locus ID | 114875 |
| Gene Summary | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.[UniProtKB/Swiss-Prot Function] |
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