Cyfip1 (NM_001164661) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR222940L4V

  • LentiORF®

Lenti ORF particles, Cyfip1 (GFP-tagged) - Mouse cytoplasmic FMR1 interacting protein 1 (Cyfip1), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 20,045.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Cyfip1 (NM_001164661) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms E030028J09Rik; l(7)1Rl; l7Rl1; l71Rl; mKIAA0068; P140SRA-1; P140sra1; pl-1; Shyc; Sra-1; Sra1
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_001164661
ORF Size 3759 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR222940).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001164661.1, NP_001158133.1
RefSeq Size 6524 bp
RefSeq ORF 3762 bp
Locus ID 20430
Gene Summary Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (PubMed:27605705).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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