Atg16l1 (NM_029846) Mouse Tagged ORF Clone Lentiviral Particle

CAT＃: MR222915L4V

  • LentiORF®

Lenti ORF particles, Atg16l1 (GFP-tagged) - Mouse autophagy-related 16-like 1 (yeast) (Atg16l1), transcript variant 2, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Datasheet
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CNY 11,970.00

货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Atg16l1 (NM_029846) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 1500009K01Rik; Apg16l; Atg16l; WDR30
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_029846
ORF Size 1821 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR222915).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_029846.4, NP_084122.2
RefSeq Size 3066 bp
RefSeq ORF 1824 bp
Locus ID 77040
Gene Summary Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane (PubMed:18849966, PubMed:12665549, PubMed:24954904, PubMed:24553140, PubMed:23392225). Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production (By similarity). Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response (PubMed:24238340). Instead, promotes with NOD2 an autophagy-dependent antibacterial pathway. Plays a role in regulating morphology and function of Paneth cell.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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