Atg16l1 (NM_029846) Mouse Untagged Clone
CAT#: MC219638
Atg16l1 (untagged) - Mouse autophagy-related 16-like 1 (yeast) (Atg16l1), transcript variant 2, (10ug)
CNY 7,790.00
Product images
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Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | 1500009K01Rik; Apg16l; Atg16l; WDR30 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC219638 representing NM_029846
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCGTCGGGCCTGCGCGCCGCAGACTTTCCCCGCTGGAAGCGTCACATCGCGGAGGAACTGAGGCGCC GGGACCGACTGCAGAGGCAGGCGTTCGAGGAGATCATTCTGCAGTATACCAAGTTGCTGGAAAAGTCAGA TCTTCATTCAGTATTGACCCAGAAACTACAAGCAGAAAAGCATGACATGCCAAATAGGCATGAAATAAGT CCTGGACATGATGGTGCGTGGAATGATAGTCAACTACAAGAAATGGCCCAGTTGAGGATCAAACACCAGG AAGAGCTGACCGAACTGCACAAGAAGCGTGGGGAGTTAGCTCAGTTGGTGATTGACCTGAACAACCAAAT GCAGCAGAAGGACAAGGAGATACAGATGAATGAAGCAAAGATTTCGGAGTATTTACAGACCATCTCTGAC CTGGAGACAAACTGCCTGGACCTGCGCACCAAACTGCAGGACCTCGAGGTAGCCAACCAGACCCTGAAGG ATGAGTATGACGCCCTGCAGATTACTTTTACTGCCCTAGAAGAGAAACTGAGGAAAACTACTGAGGAGAA CCAGGAACTGGTCACCAGATGGATGGCTGAGAAGGCCCAAGAAGCCAATCGCCTCAATGCAGAGAATGAG AAGGACTCCAGGAGGCGTCAAGCACGGCTGCAGAAGGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCTG TTGAACAGGATGATGACATTGAAGTCATTGTGGATGAGACCTCAGACCACACAGAAGAGACCTCTCCCGT CCGAGCTGTCAGCAGAGCAGCTACTAAGCGACTCTCGCAGCCTGCTGGAGGCCTTCTGGATTCTATCACT AATATCTTTGGGAGACGCTCTGTCTCTTCCATCCCAGTCCCCCAGGATATCATGGACACTCATCCTGCTT CTGGTAAAGATGTGAGAGTCCCAACTACTGCCTCGTATGTCTTCGATGCGCATGACGGAGAGGTCAACGC AGTGCAGTTCAGTCCAGGCTCCCGGTTGCTGGCCACTGGAGGCATGGACCGCAGGGTGAAACTTTGGGAA GCATTCGGAGATAAATGTGAATTCAAGGGCTCCCTGTCTGGCAGTAATGCTGGAATTACAAGCATTGAAT TTGATAGTGCTGGAGCTTACCTATTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGA TTATCGATTACGGCACACACTCACAGGCCACAGCGGGAAAGTCCTCTCTGCCAAGTTCCTGCTGGACAAT GCACGGATTGTCTCAGGAAGTCACGACCGGACCCTCAAACTCTGGGATCTCCGCAGCAAAGTCTGCATAA AAACAGTGTTTGCAGGATCCAGCTGCAATGACATTGTTTGCACTGAACAATGTGTAATGAGTGGACATTT TGACAAGAAAATTCGTTTCTGGGATATCCGGTCAGAGAGTGTGGTCCGAGAGATGGAACTGTTAGGGAAG ATCACTGCTCTGGACCTAAACCCTGAGAGAACTGAGCTCCTGAGCTGCTCCCGTGATGACCTGCTAAAAG TCATCGACCTCCGGACAAATGCAGTCAAACAGACATTCAGTGCGCCTGGATTCAAATGCGGCTCTGACTG GACCCGGGTTGTCTTCAGCCCTGATGGCAGTTACGTGGCAGCAGGCTCAGCCGAGGGTTCTCTTTATGTC TGGAGTGTGCTGACAGGGAAAGTGGAGAAGGTTCTTTCAAAACAGCACAGCTCTTCTATCAATGCGGTGG CGTGGGCCCCCTCGGGCTTACATGTTGTCAGTGTGGACAAAGGAAGCAGAGCTGTGCTGTGGGCACAGCC TTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_029846 |
Insert Size | 1824 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_029846.4, NP_084122.2 |
RefSeq Size | 3149 bp |
RefSeq ORF | 1824 bp |
Locus ID | 77040 |
UniProt ID | Q8C0J2 |
Gene Summary | Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane (PubMed:18849966, PubMed:12665549, PubMed:24954904, PubMed:24553140, PubMed:23392225). Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production (By similarity). Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response (PubMed:24238340). Instead, promotes with NOD2 an autophagy-dependent antibacterial pathway. Plays a role in regulating morphology and function of Paneth cell.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2, also known as Apg16Lbeta) lacks an exon in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2, also known as Apg16Lbeta) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG222915 | Atg16l1 (tGFP-tagged) - Mouse autophagy-related 16-like 1 (yeast) (Atg16l1) transcript variant b, (10ug) |
CNY 6,650.00 |
|
MR222915 | Atg16l1 (Myc-DDK-tagged) - Mouse autophagy-related 16-like 1 (yeast) (Atg16l1), transcript variant 2 |
CNY 6,080.00 |
|
MR222915L3 | Lenti ORF clone of Atg16l1 (Myc-DDK-tagged) - Mouse autophagy-related 16-like 1 (yeast) (Atg16l1), transcript variant 2 |
CNY 7,980.00 |
|
MR222915L4 | Lenti ORF clone of Atg16l1 (mGFP-tagged) - Mouse autophagy-related 16-like 1 (yeast) (Atg16l1), transcript variant 2 |
CNY 7,980.00 |
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