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Tfe3 (NM_001105196) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR222642L4V
- LentiORF®
-
Lenti ORF particles, Tfe3 (GFP-tagged) - Mouse transcription factor E3 (Tcfe3), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 11,115.00
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Specifications
| Product Data | |
| Product Name | Tfe3 (NM_001105196) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | bHLHe33; F830016E06Rik; Tcfe3; Tfe-3 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001105196 |
| ORF Size | 1611 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR222642).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001105196.1, NP_001098666.1 |
| RefSeq Size | 3188 bp |
| RefSeq ORF | 1614 bp |
| Locus ID | 209446 |
| Gene Summary | Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3') (PubMed:16936731). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF (PubMed:16936731). In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity (PubMed:16936731). Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer (By similarity). It also binds very well to a USF/MLTF site (By similarity). May regulate lysosomal positioning in response to nutrient deprivation by promoting the expression of PIP4P1 (PubMed:29146937).[UniProtKB/Swiss-Prot Function] |
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