Glra3 (NM_080438) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR222143L3V
- LentiORF®
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Lenti ORF particles, Glra3 (Myc-DDK-tagged) - Mouse glycine receptor, alpha 3 subunit (Glra3), 200ul, >10^7 TU/mL
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CNY 9,310.00
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Specifications
Product Data | |
Product Name | Glra3 (NM_080438) Mouse Tagged ORF Clone Lentiviral Particle |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_080438 |
ORF Size | 1440 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR222143).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_080438.2, NP_536686.2 |
RefSeq Size | 1474 bp |
RefSeq ORF | 1443 bp |
Locus ID | 110304 |
Gene Summary | Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:15131310, PubMed:20978350). Channel characteristics depend on the subunit composition; heteropentameric channels display faster channel closure (By similarity). Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents (PubMed:15131310). Contributes to increased pain perception in response to increased prostaglandin E2 levels (PubMed:15131310). Plays a role in the regulation of breathing rhythm, especially of the duration of the postinspiratory phase (PubMed:20978350). Plays a role in cellular responses to ethanol (By similarity).[UniProtKB/Swiss-Prot Function] |
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