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Ago3 (NM_153402) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR221842L3V
- LentiORF®
-
Lenti ORF particles, Ago3 (Myc-DDK-tagged) - Mouse eukaryotic translation initiation factor 2C, 3 (Eif2c3), 200ul, >10^7 TU/mL
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CNY 13,585.00
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Specifications
| Product Data | |
| Product Name | Ago3 (NM_153402) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AW048688; C130014L07Rik; Eif2c3 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_153402 |
| ORF Size | 2583 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR221842).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_153402.2, NP_700451.2 |
| RefSeq Size | 7635 bp |
| RefSeq ORF | 2583 bp |
| Locus ID | 214150 |
| Gene Summary | Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4 (PubMed:19174539). Possesses RNA slicer activity but only on select RNAs bearing 5'- and 3'-flanking sequences to the region of guide-target complementarity (By similarity).[UniProtKB/Swiss-Prot Function] |
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