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Fkbp8 (NM_010223) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR220865L4V
- LentiORF®
-
Lenti ORF particles, Fkbp8 (GFP-tagged) - Mouse FK506 binding protein 8 (Fkbp8), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | Fkbp8 (NM_010223) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 38kDa; FKBP-8; FKBP-38; Fkbp38 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_010223 |
| ORF Size | 1206 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR220865).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_010223.2, NP_034353.2 |
| RefSeq Size | 1727 bp |
| RefSeq ORF | 1209 bp |
| Locus ID | 14232 |
| Gene Summary | Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis (By similarity). Required for normal embryonic development.[UniProtKB/Swiss-Prot Function] |
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