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Fkbp8 (NM_010223) Mouse Tagged ORF Clone
CAT＃: MR220865
- TrueORF®
Fkbp8 (Myc-DDK-tagged) - Mouse FK506 binding protein 8 (Fkbp8), transcript variant 2
ORF Plasmid: tGFP
"NM_010223" in other vectors (5)
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CNY 3,656.00
| Cited in 1 publication. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | 38kDa; FKBP-8; FKBP-38; Fkbp38 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR220865 representing NM_010223
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGTCTTGGGCTGAGCCCTCTGAGCCTGCTGCCCTGCGACTTCCTGGGGCCCCACTGCTGGAGGGCT TTGAGGTGCTCGATGGGGTTGATGATGCAGAGGAGGAAGATGACCTAAGTGGGCTGCCACCACTAGAGGA CATGGGACAGCCTACAGTGGAGGAGGCTGAGCAGCCTGGAGCCCTGGCTCGGGAGTTCCTGGCAGCCACA GAGCCTGAGCCAGCCCCAGCCCCAGCCCCGGAAGAGTGGCTGGACATTCTGGGGAACGGATTGCTGCGGA TGAAGACACTGGTCCCAGGCCCGAAAGGCTCTAGCCGCCCACTCAAGGGCCAGGTGGTGACCGTTCACCT GCAGATGTCCCTGGAGAATGGCACCCGTGTACAGGAAGAGCCTGAACTGGCCTTCACGCTGGGAGACTGC GATGTTATCCAGGCCCTGGACCTCAGTGTCCCGCTCATGGATGTGGGCGAGACAGCCATGGTTACCGCTG ACTCCAAGTACTGCTACGGCCCCCAGGGCAGGAGCCCATACATCCCCCCCCACGCAGCCCTGTGCCTGGA AGTCACCCTGAAGACGGCAGAGGATGGACCCGACCTGGAGATGCTGAGTGGGCAGGAGCGCGTGGCCCTG GCCAACCGCAAGCGGGAGTGTGGCAATGCCCACTACCAGCGTGCCGACTTTGTGCTGGCCGCCAATTCCT ATGACCTGGCCATCAAGGCTATCACCTCCAACACCAAAGTGGACATGACTTGTGAGGAGGAAGAGGAGCT GCTACAGCTGAAGGTCAAGTGTCTGAACAACCTTGCGGCCTCACAGCTGAAGCTGGACCACTACCGAGCA GCTCTGCGCTCCTGTAGCCAGGTGCTGGAGCACCAGCCGGACAACATCAAGGCACTGTTCCGCAAGGGCA AGGTGCTGGCTCAGCAAGGTGAATATAGTGAGGCCATCCCAATCCTGAGGGCTGCCCTGAAGCTGGAACC TTCCAACAAGACGATCCACGCAGAGCTCTCAAAGCTGGTAAAGAAGCGTGCTGCACAGCGGAGCACAGAG ACCGCCCTGTACCGAAAGATGCTAGGCAACCCCAGCCGGCTGCCTGCCAAGTGTCCGGGAAAGGGGGCCT GGTCCATCCCGTGGAAATGGCTGTTTGGGGCGACTGCCGTGGCCCTGGGGGGCGTGGCTCTCTCTGTGGT CATTGCTGCCAGGAAC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR220865 representing NM_010223
Red=Cloning site Green=Tags(s) MASWAEPSEPAALRLPGAPLLEGFEVLDGVDDAEEEDDLSGLPPLEDMGQPTVEEAEQPGALAREFLAAT EPEPAPAPAPEEWLDILGNGLLRMKTLVPGPKGSSRPLKGQVVTVHLQMSLENGTRVQEEPELAFTLGDC DVIQALDLSVPLMDVGETAMVTADSKYCYGPQGRSPYIPPHAALCLEVTLKTAEDGPDLEMLSGQERVAL ANRKRECGNAHYQRADFVLAANSYDLAIKAITSNTKVDMTCEEEEELLQLKVKCLNNLAASQLKLDHYRA ALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKRAAQRSTE TALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_010223 |
| ORF Size | 1206 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_010223.2, NP_034353.2 |
| RefSeq Size | 1727 bp |
| RefSeq ORF | 1209 bp |
| Locus ID | 14232 |
| UniProt ID | O35465 |
| MW | 44 kDa |
| Gene Summary | Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis (By similarity). Required for normal embryonic development.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
FK506-binding protein-like and FK506-binding protein 8 regulate dual leucine zipper kinase degradation and neuronal responses to axon injury
,null,
The Journal of Biological Chemistry
,PubMed ID 35101451
[Fkbp8]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC218736 | Fkbp8 (untagged) - Mouse FK506 binding protein 8 (Fkbp8), transcript variant 2, (10ug) |
CNY 6,940.00 |
|
| MG205407 | Fkbp8 (tGFP-tagged) - Mouse FK506 binding protein 8 (Fkbp8) |
CNY 3,140.00 |
|
| MG220865 | Fkbp8 (tGFP-tagged) - Mouse FK506 binding protein 8 (Fkbp8) transcript variant 2, (10ug) |
CNY 3,140.00 |
|
| MR220865L3 | Lenti ORF clone of Fkbp8 (Myc-DDK-tagged) - Mouse FK506 binding protein 8 (Fkbp8), transcript variant 2 |
CNY 4,750.00 |
|
| MR220865L4 | Lenti ORF clone of Fkbp8 (mGFP-tagged) - Mouse FK506 binding protein 8 (Fkbp8), transcript variant 2 |
CNY 4,750.00 |
