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Rnf125 (NM_026301) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR220681L4V
- LentiORF®
-
Lenti ORF particles, Rnf125 (GFP-tagged) - Mouse ring finger protein 125 (Rnf125), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | Rnf125 (NM_026301) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 4930553F04Rik |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_026301 |
| ORF Size | 420 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR220681).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_026301.2 |
| RefSeq Size | 1334 bp |
| RefSeq ORF | 423 bp |
| Locus ID | 67664 |
| Gene Summary | E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins, such as DDX58/RIG-I, MAVS/IPS1, IFIH1/MDA5, JAK1 and p53/TP53. Acts as a negative regulator of type I interferon production by mediating ubiquitination of DDX58/RIG-I at 'Lys-181', leading to DDX58/RIG-I degradation. Mediates ubiquitination and subsequent degradation of p53/TP53. Mediates ubiquitination and subsequent degradation of JAK1. Acts as a positive regulator of T-cell activation.[UniProtKB/Swiss-Prot Function] |
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