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Ptpa (NM_138748) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR219967L3V
- LentiORF®
-
Lenti ORF particles, Ppp2r4 (Myc-DDK-tagged) - Mouse protein phosphatase 2A, regulatory subunit B (PR 53) (Ppp2r4), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Ptpa (NM_138748) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 2610042B21Rik; C77440; N28142; Ppp2r4; PR53 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_138748 |
| ORF Size | 969 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR219967).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_138748.5, NP_620087.3 |
| RefSeq Size | 2577 bp |
| RefSeq ORF | 972 bp |
| Locus ID | 110854 |
| Gene Summary | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A (By similarity).[UniProtKB/Swiss-Prot Function] |
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