United States
Germany
Japan
United Kingdom
China
Zfand2b (NM_001159906) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR217148L3V
- LentiORF®
-
Lenti ORF particles, Zfand2b (Myc-DDK-tagged) - Mouse zinc finger, AN1 type domain 2B (Zfand2b), transcript variant 3, 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 7,410.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Zfand2b (NM_001159906) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 1110060O18Rik; C81256 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001159906 |
| ORF Size | 774 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR217148).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001159906.1, NP_001153378.1 |
| RefSeq Size | 1203 bp |
| RefSeq ORF | 774 bp |
| Locus ID | 68818 |
| Gene Summary | Plays a role in protein homeostasis by regulating both the translocation and the ubiquitin-mediated proteasomal degradation of nascent proteins at the endoplasmic reticulum (PubMed:24160817, PubMed:26337389, PubMed:26692333). It is involved in the regulation of signal-mediated translocation of proteins into the endoplasmic reticulum (PubMed:24160817). It also plays a role in the ubiquitin-mediated proteasomal degradation of proteins for which signal-mediated translocation to the endoplasmic reticulum has failed (PubMed:18467495, PubMed:26337389). May therefore function in the endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for proteasomal degradation (PubMed:24160817, PubMed:26337389). By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway (PubMed:26692333).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
其它Zfand2b产品
Customer
Reviews
Loading...
