Cdk12 (NM_001109628) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR215624L4V

  • LentiORF®

Lenti ORF particles, Cdk12 (GFP-tagged) - Mouse cyclin-dependent kinase 12 (Cdk12), transcript variant 2, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 22,800.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Cdk12 (NM_001109628) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 1810022J16Rik; AI646528; Crk7; Crkrs; D11Ertd752e; Pksc
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_001109628
ORF Size 4425 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR215624).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001109628.1, NP_001103098.1
RefSeq Size 7642 bp
RefSeq ORF 4428 bp
Locus ID 69131
Gene Summary Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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