Hpf1 (NM_028299) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR212701L3V
- LentiORF®
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Lenti ORF particles, 2700029M09Rik (Myc-DDK-tagged) - Mouse RIKEN cDNA 2700029M09 gene (2700029M09Rik), 200ul, >10^7 TU/mL
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CNY 7,410.00
货期*
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规格
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经常一起买 (2)
Specifications
Product Data | |
Product Name | Hpf1 (NM_028299) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 2700029M09Rik; C4orf27; C230006B22Rik |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_028299 |
ORF Size | 1038 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR212701).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_028299.1 |
RefSeq Size | 1210 bp |
RefSeq ORF | 1041 bp |
Locus ID | 72612 |
Gene Summary | Acts as a cofactor for serine ADP-ribosylation by conferring serine specificity on PARP1 and PARP2: interacts with PARP1 and PARP2 and is able to change amino acid specificity toward serine. Promotes histone serine ADP-ribosylation in response to DNA damage, limiting DNA damage-induced PARP1 hyper-automodification, and ensuring genome stability. Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in response to DNA damage. HPF1 also promotes tyrosine ADP-ribosylation, probably by conferring tyrosine specificity on PARP1.[UniProtKB/Swiss-Prot Function] |
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