United States
Germany
Japan
United Kingdom
China
Rcor1 (NM_198023) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR212462L4V
- LentiORF®
-
Lenti ORF particles, Rcor1 (GFP-tagged) - Mouse REST corepressor 1 (Rcor1), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 8,360.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Rcor1 (NM_198023) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 5730409O11; 6720480E22Rik; AU042633; D12Wsu95e; mKIAA0071; Rocr1 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_198023 |
| ORF Size | 1146 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR212462).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_198023.2, NP_932140.1 |
| RefSeq Size | 2725 bp |
| RefSeq ORF | 1149 bp |
| Locus ID | 217864 |
| Gene Summary | Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
