Lrp6 (NM_008514) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR212053L4V

  • LentiORF®

Lenti ORF particles, Lrp6 (GFP-tagged) - Mouse low density lipoprotein receptor-related protein 6 (Lrp6), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 24,605.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Lrp6 (NM_008514) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms C030016K15Rik; Cd; Gw; ska26; ska; skax26
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_008514
ORF Size 4839 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR212053).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_008514.4, NP_032540.2
RefSeq Size 9368 bp
RefSeq ORF 4842 bp
Locus ID 16974
Gene Summary Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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