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Xpo1 (NM_001035226) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR211584L3V
- LentiORF®
-
Lenti ORF particles, Xpo1 (Myc-DDK-tagged) - Mouse exportin 1, CRM1 homolog (yeast) (Xpo1), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 16,055.00
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规格
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Specifications
| Product Data | |
| Product Name | Xpo1 (NM_001035226) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AA420417; Crm1; Exp1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001035226 |
| ORF Size | 3213 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR211584).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001035226.1, NP_001030303.1 |
| RefSeq Size | 4906 bp |
| RefSeq ORF | 3216 bp |
| Locus ID | 103573 |
| Gene Summary | Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase Ran in its active GTP-bound form. Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Involved in U3 snoRNA transport from Cajal bodies to nucleoli. Binds to late precursor U3 snoRNA bearing a TMG cap (By similarity).[UniProtKB/Swiss-Prot Function] |
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