Clstn1 (BC053843) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR211346L4V

  • LentiORF®

Lenti ORF particles, Clstn1 (GFP-tagged) - Mouse calsyntenin 1 (cDNA clone MGC:54504 IMAGE:6315355), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 13,205.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Clstn1 (BC053843) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms Cstn1, 1810034E21Rik, Cst-1
Vector pLenti-C-mGFP-P2A-Puro
ACCN BC053843
ORF Size 2907 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR211346).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq BC053843.1
RefSeq Size 4486 bp
RefSeq ORF 2909 bp
Locus ID 65945
Gene Summary Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. As intracellular fragment AlcICD, suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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