Clstn1 (BC053843) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR211346L4V
- LentiORF®
Lenti ORF particles, Clstn1 (GFP-tagged) - Mouse calsyntenin 1 (cDNA clone MGC:54504 IMAGE:6315355), 200ul, >10^7 TU/mL
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CNY 13,205.00
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Specifications
Product Data | |
Product Name | Clstn1 (BC053843) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | Cstn1, 1810034E21Rik, Cst-1 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | BC053843 |
ORF Size | 2907 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR211346).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | BC053843.1 |
RefSeq Size | 4486 bp |
RefSeq ORF | 2909 bp |
Locus ID | 65945 |
Gene Summary | Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. As intracellular fragment AlcICD, suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals.[UniProtKB/Swiss-Prot Function] |
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