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Sart3 (NM_016926) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR211322L4V
- LentiORF®
-
Lenti ORF particles, Sart3 (GFP-tagged) - Mouse squamous cell carcinoma antigen recognized by T-cells 3 (Sart3), 200ul, >10^7 TU/mL
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CNY 16,435.00
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Specifications
| Product Data | |
| Product Name | Sart3 (NM_016926) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AU045857; mKIAA0156 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_016926 |
| ORF Size | 2886 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR211322).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_016926.1 |
| RefSeq Size | 3586 bp |
| RefSeq ORF | 2889 bp |
| Locus ID | 53890 |
| Gene Summary | U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation. Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites. May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. Recruits USP4 to ubiquitinated PRPF3 within the U4/U5/U6 tri-snRNP complex, promoting PRPF3 deubiquitination and thereby regulating the spliceosome U4/U5/U6 tri-snRNP spliceosomal complex disassembly. May also recruit the deubiquitinase USP15 to histone H2B and mediate histone deubiquitination, thereby regulating gene expression and/or DNA repair (By similarity). May play a role in hematopoiesis probably through transcription regulation of specific genes including MYC (PubMed:21447833).[UniProtKB/Swiss-Prot Function] |
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