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Mastl (NM_025979) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR211003L4V
- LentiORF®
-
Lenti ORF particles, Mastl (GFP-tagged) - Mouse microtubule associated serine/threonine kinase-like (Mastl), 200ul, >10^7 TU/mL
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CNY 15,200.00
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规格
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Specifications
| Product Data | |
| Product Name | Mastl (NM_025979) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 2700091H24Rik; C88295; GW; GWL; MAST-L; THC2 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_025979 |
| ORF Size | 2595 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR211003).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_025979.4, NP_080255.3 |
| RefSeq Size | 4652 bp |
| RefSeq ORF | 2598 bp |
| Locus ID | 67121 |
| Gene Summary | Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited (By similarity).[UniProtKB/Swiss-Prot Function] |
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