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Kdm1b (NM_172262) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR210840L3V
- LentiORF®
-
Lenti ORF particles, Kdm1b (Myc-DDK-tagged) - Mouse lysine (K)-specific demethylase 1B (Kdm1b), 200ul, >10^7 TU/mL
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CNY 13,205.00
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规格
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Specifications
| Product Data | |
| Product Name | Kdm1b (NM_172262) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 4632428N09Rik; AI482520; Aof1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_172262 |
| ORF Size | 2481 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR210840).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_172262.1, NP_758466.1 |
| RefSeq Size | 4987 bp |
| RefSeq ORF | 2481 bp |
| Locus ID | 218214 |
| Gene Summary | Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4.[UniProtKB/Swiss-Prot Function] |
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