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Smurf1 (NM_029438) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR210325L3V
- LentiORF®
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Lenti ORF particles, Smurf1 (Myc-DDK-tagged) - Mouse SMAD specific E3 ubiquitin protein ligase 1 (Smurf1), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 12,065.00
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Specifications
| Product Data | |
| Product Name | Smurf1 (NM_029438) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 4930431E10Rik; mKIAA1625 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_029438 |
| ORF Size | 2184 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR210325).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_029438.3, NP_083714.3 |
| RefSeq Size | 5324 bp |
| RefSeq ORF | 2187 bp |
| Locus ID | 75788 |
| Gene Summary | E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway (By similarity). Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway (By similarity). Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA (By similarity). Promotes ubiquitination and subsequent proteasomal degradation of MAVS (PubMed:23087404). Plays a role in dendrite formation by melanocytes (By similarity).[UniProtKB/Swiss-Prot Function] |
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