Sarm1 (NM_172795) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR210296L4V

  • LentiORF®

Lenti ORF particles, Sarm1 (GFP-tagged) - Mouse sterile alpha and HEAT/Armadillo motif containing 1 (Sarm1), transcript variant 2, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 13,395.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Sarm1 (NM_172795) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms A830091I15Rik; C78606; MyD885; Sarm
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_172795
ORF Size 2172 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR210296).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_172795.3, NP_766383.2
RefSeq Size 5044 bp
RefSeq ORF 2175 bp
Locus ID 237868
Gene Summary Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury. Promotes Wallerian degeneration an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site. Can activate neuronal death in response to stress. Regulates dendritic arborization through the MAPK4-JNK pathway. Involved in innate immune response. Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38. Can restrict West Nile virus (WNV) pathogenesis.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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