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Ngly1 (NM_021504) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR209772L3V
- LentiORF®
-
Lenti ORF particles, Ngly1 (Myc-DDK-tagged) - Mouse N-glycanase 1 (Ngly1), 200ul, >10^7 TU/mL
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CNY 11,210.00
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Specifications
| Product Data | |
| Product Name | Ngly1 (NM_021504) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 1110002C09Rik; Png1; PNGase |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_021504 |
| ORF Size | 1956 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR209772).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_021504.2 |
| RefSeq Size | 2901 bp |
| RefSeq ORF | 1956 bp |
| Locus ID | 59007 |
| Gene Summary | Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins.[UniProtKB/Swiss-Prot Function] |
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